The additive value of double inversion recovery magnetic resonance sequence in diagnosing brain lesions of multiple sclerosis

Congress:

ECR 2023

Poster Number:

C-25403

Type:

Scientific Exhibit

Keywords:

CNS, Neuroradiology brain, MR, Diagnostic procedure, Imaging sequences, Sclerosis, Education and training, Outcomes

Authors:

K. A. Amin Mohamed, H. Hafez, S. A. Hassanein

DOI:

10.26044/ecr2023/C-25403

DOI-Link:

https://dx.doi.org/10.26044/ecr2023/C-25403

Methods and materials

This prospective study included fifty patients referred to the MRI unit with clinical diagnosis of multiple sclerosis. All patients underwent MRI brain examination on 1.5 T magnetic field MRI machine. Routine conventional MRI study included axial T1, T2 and FLAIR, sagittal T2, coronal FLAIR and post contrast axial, sagittal and coronal T1. additional coronal double inversion recovery was added in the precontrast series.

Image Analysis

All examinations were analysed done by two independent radiologists with 7 years and 15 years of experience respectively where any foci of high signal intensity with a size of ⩾2 mm were considered MS lesions. Counting of these lesions in each of the three sequences (T2, FLAIR, DIR) was performed separately. Classification of lesions number according to the location into three categories (A) Periventricular; including periventricular and deep WM lesions (figure 1)

Fig 1: Axial T2WI shows two T2WI hyperintense multiple sclerosis plaques at the right...

, (B) juxtacortical and cortical lesions (in the WM abutting the cortex), (figure 3 and 4)

Fig 3: A 42-year-old female with RRMS. Coronal T2 and DIR show better depiction of...

Fig 4: A 22-year-old female with PPMS. Coronal T2 and Coronal DIR at the parietal and...

, and finally (C) infratentorial lesions (figure 5).

Fig 5: A 22 year-old male with PPMS; Coronal T2WIs show extensive periventricular and...

Fig 1: Axial T2WI shows two T2WI hyperintense multiple sclerosis plaques at the right...

Fig 2: Axial DIR at a slightly higher level than figure 1 showing still the right...

Fig 3: A 42-year-old female with RRMS. Coronal T2 and DIR show better depiction of...

Fig 4: A 22-year-old female with PPMS. Coronal T2 and Coronal DIR at the parietal and...

Fig 5: A 22 year-old male with PPMS; Coronal T2WIs show extensive periventricular and...

Table 1: Table 1: Correlation between DIR detected lesions and (T2 and FLAIR) in...

Table 2: Table 2: Relation between DIR and type of multiple sclerosis. K-W:...